Structural characterization of a motor-neuron disease related protein complex
Cassandra Hayne, PhD
Gabriel Carmona Rosas, PhD
A Pilot grant for a new lab is very impactful because it allows us to explore something that we don't otherwise have funding to explore and to really give us time to focus on it.
The Pilot award is allowing us to expand our work in new directions on proteins that have a lot of relevance to what we're already doing.
AGE-seq: Antibody-Guided RNA Editing and Sequencing to Identify RNA-binding Protein Targets
Xiaochang Zhang, PhD
Xiangbin Ruan, PhD
The Pilot Award will boost our research and Xiangbin's career, presenting a great opportunity to collaborate with local experts on motor neuron diseases.
The award will propel my career as an international postdoctoral researcher, aiding our development of technology to understand RNA-protein interactions in diseases.
Investigating the potential roles of RNA granules in ALS/FTD pathogenesis with GGGGCC repeat expansion of C9ORF72
HENG-CHI LEE, PhD
Jerry Lee
Computational discovery of risk variants and genes of Amyotrophic lateral sclerosis
Xin He, PhD
ZICHENG WANG
We are doing a lot of meso development, and we can use these tools and solve some of the mysteries of these diseases. It's a learning opportunity for us to see how these tools work, their limitations, and so that we can maybe develop better tools in the future.
It's an important opportunity for us to be part of this community, to have access to different expertise, and to learn about genetics from different angles. It can eventually broaden our research scope.
Imaging synaptosome organelles and proteins to assay neurodegeneration at synapses
William Green, PhD
Theron Russell, PhD
This has been unfunded until now. It's just been a lot of big ideas that we've slowly tried to apply. But the Pilot Award will let us coalesce into more of a working group.
We're grateful to the CMND for providing us with these funds because all this research costs money, so it will be a big help.
Does m6A mRNA methylation protect against or contribute to amyotrophic lateral sclerosis?
Xiaoxi Zhuang, PhD
ZHUOYUE SHI, PhD
I've talked to Raymond Ross and Paschalis Kratsios about potential collaborations, and this is the perfect opportunity. We actually have a project to collaborate and work on. And that is the best way to make things happen.
I'm deeply honored to receive this award! It will give me the opportunity to broaden the scope of my doctoral research focusing on m6A mRNA methylation, and to gain a better understanding of neurodegenerative diseases.