A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes
Jayson J. Smith, Seth R. Taylor, Jacob A. Blum, Weidong Feng, Rebecca Collings, Aaron D. Gitler, David M. Miller III, Paschalis Kratsios. Cell Reports. 2024. doi: https://doi.org/10.1016/j.celrep.2024.113857
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Sonobe Y, Aburas J, Krishnan G, Fleming AC, Ghadge G, Islam P, Warren EC, Gu Y, Kankel MW, Brown AEX, Kiskinis E, Gendron TF, Gao FB, Roos RP, Kratsios P. Nat Commun. 2021 Oct 15;12(1):6025. doi: 10.1038/s41467-021-26303-x.
Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons.
Sonobe Y, Lee S, Krishnan G, Gu Y, Kwon DY, Gao FB, Roos RP, Kratsios P.Elife. 2023 Sep 7;12:e83189. doi: 10.7554/eLife.83189.PMID: 37675986 Free PMC article.
Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.
Catela C, Chen Y, Weng Y, Wen K, Kratsios P.Elife. 2022 Mar 22;11:e70766. doi: 10.7554/eLife.70766.PMID: 35315772 Free PMC article.