While Alzheimer’s disease usually affects people over the age of 65, it can also affect people in their 40s, 50s and early 60s. When it does, the condition is known as younger-onset or early-onset Alzheimer’s disease.

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease.

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease in a new study by investigators at the University of Chicago

UChicago researchers are studying protein misfolding and genetics in prion disease to unlock clues to Alzheimer’s, Parkinson’s, and ALS.

Proteins active in a neuron’s development can have powerful roles in its maintenance later: a “temporal modularity,” where proteins take on multiple roles at different times in a cell’s life.